The results showed that TP53, TTN, CSMD3, LRP1B, ZFHX4, XIRP2, NAV3, COL11A1, PCDH15, APOB, RP1L1, and NPAP1 gene mutations were significantly enriched in tumor tissues with high and low expression of KIAA1429 (Figure 2c). The gene discussed is RP1L1; the disease is neoplasm.