For nocturnal non-severe hypoglycemia, the RRR was 39% for treatment with insulin analogs corresponding to an ARR of 4.2 events per patient-year (p < 0.0001), and when divided into asymptomatic and symptomatic nocturnal hypoglycemia, the RRR was 28% (p < 0.001) and 48% (p < 0.0001), respectively (Agesen et al., 2016). Here, INS is linked to Hypoglycemia.