Analyses in children with a double diagnosis also demonstrated a strong positive correlation between GAL-1 and composite estimates of several cytokines, with the strongest positive correlation found when combining IL-1β, IL-6, and TNF-α, but also a positive correlation to Th1-associated IFN-γ and the T1D-associated immune marker visfatin. This evidence concerns the gene IFNG and type 1 diabetes mellitus.