Furthermore, in T1D children, the population of CD25hiCD101+, as well as the frequency of CD101 expressing CD25hi Treg cells, were both positively correlated to the concentration of GAL-1 [r = 0.77, P = 0.002 (Fig. 3b) and r = 0.63, P = 0.019 (Fig. 3c), respectively]. Here, LGALS1 is linked to type 1 diabetes mellitus.