PARS2 and hypertrophic cardiomyopathy: Cardiac involvement is commonly observed in patients with pathological variants of PARS2, usually with initial hypertrophic cardiomyopathy followed by a dilatative evolution in a brief time before death (Almuqbil et al., 2020) usually occurring in childhood (Ciara et al., 2018; Sofou et al., 2015).