CD274 and neoplasm: In the present study, the multivariable analysis identified brain metastasis (p = 0.03), 100 ≤ Eo < 500 (p = 0.01), an increased REC (p = 0.003), increased RNC (p = 0.004), tumor size ≥5 cm (p = 0.006), and PD‐L1 ≥ 1% (p = 0.03) as independent predictors of OS.