In the Cox proportional regression analysis, brain metastasis (HR, 1.70; 95% CI: 0.89–3.23; p = 0.07), 100 ≤ Eo < 500 (HR, 0.26; 95% CI: 0.07–1.11; p = 0.02), an increased REC (HR, 0.52; 95% CI: 0.29–0.82; p = 0.006), increased RNC (HR, 3.32; 95% CI: 1.25–10.3; p = 0.02), tumor size ≥5 cm (HR, 2.19; 95% CI: 1.04–4.83; p = 0.02), and PD‐L1 ≥ 1% (HR, 0.58; 95% CI: 0.31–1.03; p = 0.045) correlated with OS. Here, CD274 is linked to neoplasm.