LASSO regression resulted in a panel of six SPs for AD, including Cer d18:1/16:0, Cer d16:1/24:0, GM3 d18:1/16:0, GM3 d16:1/22:0, SM d16:1/22:0, and HexCer d18:1/18:0 (Fig. 5A). The gene discussed is CBLN1; the disease is Alzheimer disease.