Out of 77 species, 5 SPs were altered in both dementias after false discovery rate correction, including upregulation of two d18:1 SPs (Cer d18:1/16:0 and HexCer d18:1/18:0) as well as downregulation of three d16:1 SPs (Cer d16:1/24:0, GM3 d16:1/22:0, SM d16:1/22:0). Here, CBLN1 is linked to dementia.