As shown in Fig. 5B–C, the ATP function related proteins ATP5PO and NDUFA5 are upregulated, the ROS-related proteins PTEN and CAT are upregulated and downregulated, respectively, in the cardiomyocytes of COVID-19 hearts compared with the control samples, indicating that energy metabolism was abnormally active after infection. This evidence concerns the gene NDUFA5 and infection.