These proteins are involved in processes such as the fatty acid beta-oxidation (HADHB, HADHA, ECH1, and HSD17B4) and the electron transport coupled proton transport (MT-ND5 and MT-CO1), indicating that the hearts of patients with COVID-19 may consume excessive energy as a result of the SARS-CoV-2 infection. This evidence concerns the gene HSD17B4 and COVID-19.