C4B and cyclic hematopoiesis: In the univariable analysis, age (HR 1.04, 95% CI 1.01–1.06, p = 0.010), DLCO < 60% (HR 2.90, 95% CI 1.45–5.81, p = 0.003), CH (HR 2.11, 95% CI 1.21–3.69, p = 0.009), and an interaction term between CH and adjuvant therapy (HR 2.42, 95% CI 1.54–3.81, p < 0.001) were shown as significant prognostic factor for OS.