APOB and insomnia measurement: There was no heterogeneity observed in the Q variable for TG, ApoA-1, ApoB, LPA, and insomnia (Table 3, MR‒Egger Q, TG: P = 0.996, ApoA-1: P = 0.892, ApoB: P = 0.601, LPA: P = 0.339).