The meta-analysis of the DEPs in AH between AMD patients and healthy controls is shown in Fig. 4: apolipoprotein A1 (APOA1, P02647), apolipoprotein A4 (APOA4, P06727), complement C3 (C3, P01024), clusterin (CLU, P10909), cathepsin D (CTSD, P07339), lipocalin-1 (LCN1, P31025), pigment epithelium-derived factor (PEDF, P36955), prostaglandin-H2 D-isomerase (PTGDS or PH2D, P41222) and kallistatin (SERPINA4, P29622) (gene names and accession numbers, respectively). The gene discussed is C3; the disease is age-related macular degeneration.