Older age, DM, end stage renal disease (ESRD), elevated white blood cell count (WBC), aspartate transaminase (AST), alanine transaminase (ALT), blood urea nitrogen (BUN), creatinine, C-reactive protein (CRP), and physical activity status were significantly different between patients with PEG insertions and cholelithiasis and those without cholelithiasis (p < 0.05) (Table 1). The gene discussed is CRP; the disease is chronic kidney disease.