IGF1 and necrotizing enterocolitis: Nine IGF-1 pigs and 17 control pigs died or were euthanized ahead of the predetermined end of the experiment due to respiratory distress (3/26: one IGF-1, two controls), clinical gastrointestinal symptoms with feeding intolerance and/or signs of NEC (18/26: six IGF-1, 12 controls), unknown cause (1/26, one control) and catheter-related problems (two IGF-1, two controls).