Reanalysis of microarray data obtained from renal biopsy specimens of patients with CKD (GSE66494) showed that the expression levels of PFKP (P < 0.001) and FN1 (a fibrogenic gene) were significantly increased in kidney samples from patients with CKD compared with those from healthy controls (Fig. 1A). The gene discussed is PFKP; the disease is chronic kidney disease.