Many of these genes were also induced in Nrf2–/– BMDMs exposed to oxLDL, but the rescue by OI treatment was attenuated (IL-12, CCL2, and CCL5) or eliminated (e.g., IL-1β, IL-6, CCL3, CXCL1, CXCL2, and CXCL10; Figure 7E). This evidence concerns the gene CXCL2 and osteogenesis imperfecta.