CCL5 and atherosclerosis: To further investigate the impact of Acod1 deficiency on inflammation during atherogenesis, we measured the aortic gene expression of the following 9 proinflammatory cytokines and chemokines that have been implicated in atherosclerosis: IL-1β, IL-6, IL-12, CCL2, CCL3, CCL5, CXCL1, CXCL2, and CXCL10 (25, 28, 29).