Macrophage proliferation within plaques can contribute to atherosclerosis, especially at later stages (39–41), but c7 (G2/M macrophages) was comparable between WT and Acod1–/–, whereas c6 (G1 macrophages) was decreased in Acod1–/– atherosclerotic aortas (Figure 3, E and F, and Supplemental Table 2). This evidence concerns the gene C6 and atherosclerosis.