To confirm the effect on the core promoter regions of these genes in cancer, we compared the methylation fraction around the promoter regions (Figure 4C, left) and the expression levels of these genes (Figure 4C, right) for diverse cancer subtypes from the DepMap portal (26); expression levels of ZNF667-AS1 were not available at the time of the analysis. The gene discussed is ZNF667; the disease is cancer.