In addition to the LDH/ADA ratio, the level ofADA in the pleural effusion is also part of the scoringsystem in the diagnosis of pleural effusions, whichalso includes pleural LDH, LDH/ADA ratio, the levelof serum albumin and albumin in the pleural punctate,the cell type of the pleural punctate, etc. In aChinese retrospective study, it was shown that cut-offvalues of ADA > 19.65 U/L, LDH/ADA 29.61 andS-Alb > 23.95 g/L show 100% sensitivity and 98.7%specificity for differential diagnosis TP [23]. The gene discussed is ADA; the disease is Pleural effusion.