Zhang et al. (24) investigated the effect of chromium supplementation on inflammatory biomarkers (C-reactive protein (CRP), Tumor necrosis factor (TNF-α), and Interleukin (IL-6)) in type 2 diabetes, metabolicsyndrome, obesity, and polycystic ovary syndrome. The gene discussed is CRP; the disease is obesity due to melanocortin 4 receptor deficiency.