Bakke et al. (2019) identified PSMA6 (proteasome 20S subunit alpha 6) in pancreatic cell lines and validated its role in pancreatic cancer cell lines and found that the knockout of PSMA6, as a proteasomal subunit of the 20S core complex, can induce apoptosis in cells. Here, PSMA6 is linked to pancreatic neoplasm.