Results from Cell Counting Kit-8 (CCK-8) assay demonstrated that 769-p (Fig. 3A) and Caki-1 (Fig. 3B) cells with decreased GDF15 expression had enhanced viability compared to cells in the control knockdown group, while ectopic expression of GDF15 hindered viability of these tumor cells. This evidence concerns the gene GDF15 and neoplasm.