We already know that germline protein truncation variants (PTV) and rare missense variants (MSV) in nine genes, i.e., AMT, BRCA1, BRCA2, CHEK2, PALB2, BARD1, RAD51C, RAD51D, and TP53, are reportedly strongly associated with BC development [2]. The gene discussed is RAD51D; the disease is breast cancer.