The gene signatures enriched in these processes were visualized between PCa (CCL21, THBS1, PTPRC, TNFSF14, CD3E), CAFs (CCL19, THBS1, CD3E) and TLN (CCL19, CTLA4, PTPRC, TNFSF14, ITK, CD3E) (Fig. 5I). The gene discussed is ITK; the disease is posterior cortical atrophy.