Previous research has demonstrated that the CSGALNACT2 expression was positively associated with the level of immune cells (including dendritic cell, neutrophil, macrophage, CD4+T Cell, and CD8+T Cell), and high expression of CSGALNACT2 was significantly associated with shorter overall survival (OS) rate in COAD and READ [23]. The gene discussed is CD8A; the disease is colon adenocarcinoma.