SIRT6 and breast cancer: Accordingly, Kaplan–Meier plots from GOBO show that basal-like breast cancer patients with high expression of SIRT6 (red line, n = 70) have better prognosis in terms of RFS (Fig. S8C, Log-rank test, p = 0.04656) than patients expressing low levels of SIRT6 (grey line, n = 73).