MDA-MB-468 cells were more sensitive to DXR and PTX than MDA-MB-231 cells, indicating that the basal subtype of breast cancer is more sensitive to chemotherapy than the claudin-low subtype [27, 28], and the combination of Mint3 depletion and chemotherapy strikingly reduced tumor volumes in these cells (Fig. 3D, E). This evidence concerns the gene APBA3 and breast cancer.