In terms of OS, patients with age >60 years, male patients, patients who drinked, patients without hypertension, patients with ECOG PS score 1, patients with moderate tumour differentiation, patients with LYN metastasis, patients with CEA > 5 ng/mL, patients with CA125 > 35 U/mL, patients with chemotherapy and patients with adjuvant chemotherapy were suitable populations to use RGS1 > 3.980 or RGS1 > 3.685 for estimating OS (supporting information Table S3). Here, MUC16 is linked to hypertensive disorder.