In this analysis of the BACC study, we investigated the prognostic utility of 29 biomarkers based on an ML-based approach and identified three of them—NT-proBNP, Apo A-I and KIM-1—as best-predictive biomarkers for 1-year MACE in an unselected cohort of patients with suspected MI. The gene discussed is HAVCR1; the disease is myocardial infarction.