ACSL4 and breast cancer: Untargeted lipidomic analyses revealed that ACSL4 knockdown breast cancer cells had a reduced ability to incorporate long-strain monounsaturated (18:1, 17:1, 22:1, 24:1, and 26:1) and saturated FAs (16:0, 18:0, 24:0, and 26:0) into TG and phospholipids, indicating that ACSL4 promotes the incorporation of long-chain monounsaturated and saturated FAs into TG and phospholipids in these cells (Figure 3D, E).