All of them exhibited a significant association with the prognosis of individuals diagnosed with CRC (p<0.05), where patients in the high expression groups of AOC3 (Supplementary Figure 3A), CCS (Supplementary Figure 3B), CDKN2A (Supplementary Figure 3C), COX17 (Supplementary Figure 3E), and COX19 (Supplementary Figure 3F) exhibited unfavorable prognosis. Here, CCS is linked to colorectal carcinoma.