The logistic model that evaluated the risk factors for AKI showed that the variables age (OR 1.03; 95% CI 1.02–1.04), male sex (OR 2.13; 95% CI 1.49–3.04), DM (OR 1.55; 95% CI 1.04–2.32), CKD (OR 2.07; 95% CI 1.06–4.04), CRP at admission (OR 1.02; 95% CI 1.00-1.03), ICU admission (OR 1.81; 95% CI 1.04–3.16), and vasopressor support (OR 7.46; 95% CI 3.34–16.64) impacted the probability of developing AKI in the population and that bicarbonate (OR 0.89; 95% CI 0.84–0.94) and PaFiO2 (OR 0.99; 95% CI 0.98–0.99) were protective factors (Table 4). The gene discussed is CRP; the disease is acute kidney injury.