CBLN1 and infection: It is interesting to note that many of these lipids that increased in sEVs derived from infected cells were also identified in uninfected cells [including Cer(d18:2/24:1), Co(Q8), Cer(d34:1), PC(14:0_20:4), PC(15:0_20:3), PC(18:2_20:4), PE(20:1_20:4), PI(36:4), or PC(O-16:1/18:2], so while it is possible that bacteria contribute lipid content of host-derived sEVs during infection, all of the lipids increased in sEVs derived from infected cells were also identified in sEVs from uninfected cells.