SOAT1 and Duchenne muscular dystrophy: Importantly, despite the observed heterogeneity of the samples, changes in gene expression still translated to the common altered pathways in DMD cells, among which were those described to regulate cardiomyocyte physiology, e.g. JAK-STAT and Hippo pathways.18,19 Moreover, GSEA demonstrated that the products of genes with altered expression in DMD hiPSC-CM perform their functions mainly within the cell membrane, extracellular matrix, and cytoskeleton.