TF and Duchenne muscular dystrophy: Namely, when saturated transferrin does not maintain the excessive iron transportation, the non-transferrin-bound iron can enter the cell through L-type calcium channels (LTCC), what may disturb the normal calcium transportation and, as a result, provoke the excitation-contraction coupling impairment.40,45 This explanation stands in line with defective calcium oscillations in DMD hiPSC-CM demonstrated in previous studies.