Down-stream targets of c-MYC relevant to endometriosis pathophysiology may include upregulated targets such as cyclin E1 (CCNE1; Park et al., 2019; Park et al., 2020), enolase 1 (ENO1; Nabeta et al., 2009), fatty acid synthase (FASN; Turathum et al., 2022), lactate dehydrogenase A (LDHA; Zheng et al., 2021), microsomal glutathione S-transferase 1 (MGST1; Ferrero et al., 2019), 60S acidic riboprotein 1 (RPLP1; Alali et al., 2020), and tumor protein p53 (TP53; Toki and Nakayama, 2000). The gene discussed is LDHA; the disease is endometriosis.