SOAT1 and endothelial dysfunction: Currently, it is widely believed that the JAK/STAT signaling pathway can regulate biological processes such as cell proliferation, differentiation, and apoptosis, and participate in various biological functions of cytokines, such as inducing the secretion of inflammatory factors, aggravating inflammatory reactions, lowering vascular relaxation, leading to endothelial dysfunction, and endothelial cell apoptosis (Hu et al., 2021; Xin et al., 2020).