Therefore, literature has reported the close correlation of abnormal activation of the JAK/STAT signaling pathway with the occurrence and development of various diseases, such as atherosclerosis, myocardial ischemia-reperfusion, nephritis (Cai et al., 2021), and arthritis (Simon et al., 2021), but there are few reports on its relationship with OSA. The gene discussed is SOAT1; the disease is arthritic joint disease.