The results showed that Lasso regression identified a total of seven genes as the characteristic genes of sleep apnea, which are: C12orf54, FOS, GPR1, OR9A4, MYO5B, RAB39B, KLHL4, as the core genes of follow-up research and construction of prediction models (Fig. 3C). The gene discussed is KLHL4; the disease is sleep apnea syndrome.