Analyze the expression differences of disease genes between groups, and found seven hub genes and ACE, ADIPOQ, AHDC1, BCHE, BDNF, CHAT, CRP, CRY1, CXCL8, EDN1, HTR2A, IL6, LEP, MECP2, PHOX2B, RET, TNF and other genes There are differences in the expression of the two groups of patients.We performed a correlation analysis on hub genes and sleep apnea-related genes. The gene discussed is PHOX2B; the disease is Sleep apnea.