First, we observed that genes that were upregulated in mock-infection vs. input were frequently downregulated in both wild-type and Δvxcl1 virus infections, such as cytokine-encoding Cxcl11, or Fdft1 and Fdps, which are both coding for enzymes in the cholesterol synthesis pathway (Figure 4B). The gene discussed is CXCL11; the disease is infection.