− 2’-5’-oligoadenylate synthetases (OAS) family includes OAS1, OAS2, OAS3, and OAS-like (OASL which is associated with viral translation) interferon-induced antiviral enzymes − Regulate the early phase of viral infection by degrading viral RNA in combination with RNaseL, resulting in the inhibition of viral replication. Here, OAS3 is linked to viral infectious disease.