Since myeloid-ILK deficiency improves body weight loss in APCmin/+ mice (Figure 3A) and cancer-associated cachexia is associated with a poor outcomes with a reduced survival rate (33, 36), it was of interest to determine whether myeloid-ILK deficiency confers a protective effect and prolonged survival in APCmin/+ mice. The gene discussed is ILK; the disease is Cachexia.