In Figures 7(i) and 7(h), we analyzed all DEGs for their GSEA which showed that PLAU and CTSK are connected with Reactome GPCR ligand binding, Reactome G alpha-1 signaling events, Reactome neuronal system, Reactome metabolism of amino acids and derivatives, Reactome class A 1 rhodopsin-like receptors, Reactome metabolism of amino acids and derivatives, Reactome translation, Reactome rRNA processing, KEGG Huntington's disease, and Reactome regulation of expression of Slits and Robos in PAAD. The gene discussed is CTSK; the disease is juvenile Huntington disease.