While the results of the multivariate analysis demonstrated that for PLAU, N1 (adjusted HR = 1.837, 95% CI = 1.059–3.187, p = 0.03) and the expression of PLAU (adjusted HR = 1.249, 95% CI = 1.062–1.470, p = 0.007) were multivariate factors of OS in patients with PAAD, while for CTSK, N1 (adjusted HR = 1.878, 95% CI = 1.070-3.295, p = 0.028) was independent factors of OS in patients with PAAD (Figures 5(c) and 5(d)). The gene discussed is CTSK; the disease is pancreatic adenocarcinoma.