EGFR and colorectal carcinoma: Besides the mentioned RTKs, several other receptors including VEGFR,235, 236 EGFR,227, 237 STYK1,238 ALK,239, 240 LMTK3,241 TIE2,242 ROS1,239, 240 IGF1R,20 TYRO3,243 and MER243 have also been found to have prognostic significance in CRC.