To validate genes associated with inter- and intratumoral heterogeneity in an independent dataset, we interrogated a GBM Visium spatial transcriptomics cohort.15 Similar to our IDH-wt cohort, PDGFRA expression was homogenous and varied between samples from 16 patients, whereas VEGFA expression displayed dynamic variability within patient samples (Figure 2E). Here, PDGFRA is linked to glioblastoma.