Although we found that genes, such as NANS, PABPC1L, PILRB, PPFIA2, and SESN3, presented consistent trends in the GS groups of ST and were associated with clinicopathological parameters and prognosis in the TCGA-PRAD dataset, discordance in the expression patterns of other genes, such as CNIH4, CRIP2, and PART1, also existed. Here, PPFIA2 is linked to prostate adenocarcinoma.