We included solid organ transplantation, antiviral drugs, antibacterial drugs, total dosage of steroids in the past month for COVID-19, APACHE II scores, SOFA scores, fever, IL-6, IL-8, CD4+ T lymphocytes, CD8+ T lymphocytes, and bronchial wall thickening in the multivariate logistic regression analysis. The gene discussed is CD4; the disease is COVID-19.