The mean cumulative number of irradiations of all their treatment cycles was the lowest (26.3 ± 14.8) for PLC and the highest (105.7 ± 17.0) for pretibial myxedema and the mean cumulative UVA1 dose, was the lowest 540.2 ± 463.4 J/cm2 for SLE and the highest 6005.5 ± 2360.4 J/cm2 for Buschke Scleredema (Table 2). The gene discussed is HSPG2; the disease is systemic lupus erythematosus.