The results of MR analysis showed that significant causal association between CCL18 [OR (95%CI), 0.961 (0.939–0.984), p = 1.13E-03], CCL19 [OR (95%CI), 0.920 (0.875–0.968), p = 1.20E-03], CCL24 [OR (95%CI), 1.058 (1.009–1.109), p = 0.02] and CXCL17 [OR (95%CI), 1.074 (1.020–1.132), p = 7.83E-03] and prostate cancer (ebi-a-GCST006085) (Figure 2). This evidence concerns the gene CCL19 and Familial prostate cancer.