Genetic variants of glutamate receptors are also linked to epilepsy, such as polymicrogyria is associated with mutations in GRIN1 (Fry et al. 2018), epilepsy-aphasia spectrum disorders with mutations in GRIN2A (Carvill et al. 2013), epilepsy and movement disorders with GRIN2B (Platzer et al. 2017), epileptic encephalopathy with GRIN2D (Li et al. 2016), and developmental epileptic encephalopathy with GRIA2 (Salpietro et al. 2019). Here, GRIN2B is linked to Epileptic encephalopathy.