IL6 and memory impairment: For example, FC produces a robust memory which is recalled for up to 2 months post-training (Pickens et al., 2009), but YM spatial memory lasts for 24 h (Hughes, 2004) and it is possible that a less robust memory is more susceptible to learning and memory impairment induced by chronic neuroinflammation in GFAP-IL6 mice.