Additionally, Alpinia oxyphylla crude polysaccharides (49) and polysaccharides of Schisandra Chinensis Fructus (50) inhibited the inflammatory response in the AD mouse model and reduced the release of pro-inflammatory factors such as Interleukin-1 beta (IL-1β) and Tumor Necrosis Factor-alpha (TNF-α). The gene discussed is TNF; the disease is Alzheimer disease.