In CRC, it was found that m6A-modified circQSOX1 function as sponge for miRNA-330-5p and miRNA-326 to augment PGAM1, which ultimately leads to immune escape via activation of glycolysis and inactivation of response against anti-cytotoxic T-lymphocyte-associated antigen-4 (CTLA-4) therapy [277]. The gene discussed is CTLA4; the disease is colorectal carcinoma.