The results showed that SNP sites such as AKR1C2 (rs116900756), AKR1D1 (rs9642092), CYP11B1 (rs1134095), CYP3A7 (rs45446698) appeared simultaneously in the MR analysis results of TT and BioT on ovarian cancer, endometrial cancer, endometriosis, PCOS and POF. Here, CYP3A7 is linked to ovarian carcinoma.