LGTB-associated immune factors (such as vascular endothelial growth factor, various cytokines, leukemia inhibitors, and cell adhesion molecules such as E cadherin, mucin-1, MECA-79, and alphavbeta3 integrin) may play a role in the implantation of the zygote by changing endometrial receptivity [10,11,12,13,14,15,16]. The gene discussed is CDH1; the disease is leukemia.