Figure 7 illustrates that Ki67 exhibited the highest diagnostic value in determining the T stage (Figure 7A), N stage (Figure 7B), organization differentiation (Figure 7C), signet ring cell carcinoma component (Figure 7F), and adenoma carcinogenesis (Figure 7G). Additionally, for the diagnosis of the mucinous carcinoma component (Figure 7H), Her-2 displayed the highest diagnostic value. MutP53 proteins demonstrated superior performance in the diagnosis of perineural invasion (Figure 7D), vascular invasion (Figure 7E), and pMMR/dMMR (Figure 7I). This evidence concerns the gene MKI67 and adenoma.